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Autoimmune hepatitis

Farhad Sahebjam,John M. Vierling

Frontiers of Medicine 2015, Volume 9, Issue 2,   Pages 187-219 doi: 10.1007/s11684-015-0386-y

Abstract:

Autoimmune hepatitis is a chronic liver disease putatively caused by loss of tolerance to hepatocyte-specificAlthough autoimmune hepatitis occurs in childhood, this review focuses on disease in adults.Since many features also occur in other chronic liver diseases, these scoring systems aid evaluationLiver transplantation represents a life-saving option for patients presenting with acute liver failureTransplant recipients are at risk for recurrent autoimmune hepatitis in the allograft, and de

Keywords： autoimmune hepatitis     autoantibodies     diagnosis     immunological diseases     drug-induced liver injury     therapy     immunosuppression     outcomes     hepatocellular carcinoma     liver transplantation    

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γδ T cells in liver diseases

Xuefu Wang, Zhigang Tian

Frontiers of Medicine 2018, Volume 12, Issue 3,   Pages 262-268 doi: 10.1007/s11684-017-0584-x

Abstract: fatty liver disease, autoimmune hepatitis, liver fibrosis and cirrhosis, and liver cancer and regenerationdiseases.We believe that determining the properties and functions of γδ T cells in liver diseasesenhances our understanding of the pathogenesis of liver diseases and is useful for the design of novelγδ T cell-based therapeutic regimens for liver diseases.

Keywords： γδT cells     liver infection     non-alcoholic fatty liver disease     autoimmune hepatitis     liver fibrosis and cirrhosis     liver cancer     liver regeneration    

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NKT cells in liver diseases

Shasha Zhu, Huimin Zhang, Li Bai

Frontiers of Medicine 2018, Volume 12, Issue 3,   Pages 249-261 doi: 10.1007/s11684-018-0622-3

Abstract: Natural killer T cells play important roles in infections, tumors, autoimmune diseases, and metabolicdiseases.biology of natural killer T cells and their roles in hepatitis B virus and hepatitis C virus infection, autoimmuneliver diseases, alcoholic liver disease, nonalcoholic fatty liver disease, and hepatocellular carcinomadiseases, which might be caused by changes in natural killer T subsets, factors skewing cytokine responses

Keywords： natural killer T cells     hepatitis B virus and hepatitis C virus infection     autoimmune liver diseases     alcoholicliver disease     nonalcoholic fatty liver disease     hepatocellular carcinoma    

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The critical importance of epigenetics in autoimmune-related skin diseases

Frontiers of Medicine 2023, Volume 17, Issue 1,   Pages 43-57 doi: 10.1007/s11684-022-0980-8

Abstract: Autoimmune-related skin diseases are a group of disorders with diverse etiology and pathophysiology involvedGenetics and environmental factors may contribute to the development of these autoimmune disorders.this review, we discuss the most recent findings regarding the function of epigenetic mechanisms in autoimmune-relatedskin disorders, including systemic lupus erythematosus, bullous skin diseases, psoriasis, and systemic

Keywords： epigenetics     autoimmune-related skin diseases     DNA methylation     histone modifications     noncoding RNAs    

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Laparoscopic treatment of liver diseases in children

Jia Wei, Jiexiong Feng

Frontiers of Medicine 2011, Volume 5, Issue 4,   Pages 388-394 doi: 10.1007/s11684-011-0165-3

Abstract: Laparoscopic liver surgery has been increasingly used for the treatment of pediatric liver diseases overnumber of factors are considered when electing to undergo the surgical process, including age, type of liverEspecially in children with liver masses, the number of trocars used and the position of their placementapplication of various laparoscopic instruments and the methods used for the laparoscopic treatment of liverdiseases in children over the past decade are summarized.

Keywords： laparoscopic surgery     liver mass     pediatric    

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Th17 Cells in autoimmune diseases

Lei Han,Jing Yang,Xiuwen Wang,Dan Li,Ling Lv,Bin Li

Frontiers of Medicine 2015, Volume 9, Issue 1,   Pages 10-19 doi: 10.1007/s11684-015-0388-9

Abstract: inflammatory diseases.Here, we summarize recent research progress on Th17 function in the development and pathogenesis of autoimmunediseases.molecule compounds to manipulate Th17 function for potential therapeutic application to treat human autoimmunediseases, including rheumatoid arthritis, systemic lupus erythematosus, Sj?

Keywords： IL-17     Th17 cells     RORγt     autoimmune diseases     posttranslational modification     inhibitors    

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Natural killer cells in liver diseases

Meijuan Zheng, Haoyu Sun, Zhigang Tian

Frontiers of Medicine 2018, Volume 12, Issue 3,   Pages 269-279 doi: 10.1007/s11684-018-0621-4

Abstract: such as liver immunity and liver tolerance.Liver tolerance plays an important role in liver diseases including acute inflammation, chronic infection, autoimmune disease, and tumors.Under the setting of liver diseases, NK cells are of great importance for stimulating or inhibiting immunediseases.

Keywords： natural killer cell     phenotype     immune activation     immune tolerance     liver diseases    

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The Gut Microbiota, Tumorigenesis, and Liver Diseases

Guishuai Lv, Ningtao Cheng, Hongyang Wang

Engineering 2017, Volume 3, Issue 1,   Pages 110-114 doi: 10.1016/J.ENG.2017.01.017

Abstract:

In recent decades, diseases concerning the gut microbiota have presented some of the most seriousmicrobiota are instrumental in determining the occurrence and progression of hepatocarcinoma, chronic liverdiseases related to alcohol, nonalcoholic fatty liver disease (NAFLD), and cirrhosis.Here, we provide an overview of the relationships among the gut microbiota, tumors, and liver diseasesbacterial homeostasis, we discuss probiotics in this article in order to guide treatments for related diseases

Keywords： Gut microbiota     Dysbiosis     Tumorigenesis     Hepatocellular carcinoma     Nonalcoholic fatty liver disease    

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Human menstrual blood-derived stem cells alleviate autoimmune hepatitis via JNK/MAPK signaling pathway

Frontiers of Medicine 2023, Volume 17, Issue 3,   Pages 534-548 doi: 10.1007/s11684-022-0953-y

Abstract: Autoimmune hepatitis (AIH) is a severe globally distributed liver disease that could occur at any agemenstrual blood-derived stem cells (MenSCs) have shown therapeutic effect in acute lung injury and liverresults showed that the mortality by Con A injection was significantly decreased by MenSCs treatment and liver

Keywords： autoimmune hepatitis (AIH)     concanavalin A (Con A)     human menstrual blood-derived stem cells (MenSCs)    

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Partial liver transplantation

Nianqiao GONG, Xiaoping CHEN

Frontiers of Medicine 2011, Volume 5, Issue 1,   Pages 1-7 doi: 10.1007/s11684-010-0105-7

Abstract:

Partial liver transplantation, including reduced-size liver transplantation, split liver transplantation, and living donor liver transplantation, has been developed with several innovative techniques becauseSplit liver transplantation provides chances to two or even more recipients when only one liver graftBefore surgery, a series of donor evaluations—including anatomical, liver volume, and liver functionAt different recipient conditions, auxiliary liver transplantation and auxiliary partial orthotopic liver

Keywords： partial liver transplantation     reduced-size liver transplantation     split liver transplantation     living donorliver transplantation    

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Diagnostic criteria of latent autoimmune diabetes in adults (LADA): a review and reflection

Yu Liao, Yufei Xiang, Zhiguang Zhou

Frontiers of Medicine 2012, Volume 6, Issue 3,   Pages 243-247 doi: 10.1007/s11684-012-0201-y

Abstract: Latent autoimmune diabetes in adults (LADA) is a subtype of autoimmune diabetes.Here, we aim to review and discuss the diagnostic criteria of latent autoimmune diabetes in adults.

Keywords： LADA     diagnostic criteria     autoantibodies     insulin independence     age of diagnosis    

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Autoimmune regulator regulates autophagy in THP-1 human monocytes

Liang SHI, Li-Hua HU, Yi-Rong LI

Frontiers of Medicine 2010, Volume 4, Issue 3,   Pages 336-341 doi: 10.1007/s11684-010-0096-4

Abstract: The autoimmune regulator (AIRE) is a crucial factor for the induction of central tolerance, and mutations

Keywords： autoimmune regulator     autophagy     monocytes     light chain 3 (LC3)    

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The “Traditional Chinese medicine regulating liver regeneration” treatment plan for reducing mortalityof patients with hepatitis B-related liver failure based on real-world clinical data

Ling Dai, Xiang Gao, Zhihua Ye, Hanmin Li, Xin Yao, Dingbo Lu, Na Wu

Frontiers of Medicine 2021, Volume 15, Issue 3,   Pages 495-505 doi: 10.1007/s11684-020-0790-9

Abstract: explore the effect and mechanisms of the treatment plan of “traditional Chinese medicine (TCM) regulating liverA total of 457 patients with HBV-related liver failure were retrospectively collected.In addition, there were significant differences in the expression of several cytokines related to liverRLR treatment can decrease jaundice, improve liver function, and significantly reduce the mortality inpatients with HBV-related liver failure.

Keywords： hepatitis B virus-related liver failure     traditional Chinese medicine     liver regeneration     liver regeneration    

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Assessment of liver volume variation to evaluate liver function

Cong Tong, Xinsen Xu, Chang Liu, Tianzheng Zhang, Kai Qu

Frontiers of Medicine 2012, Volume 6, Issue 4,   Pages 421-427 doi: 10.1007/s11684-012-0223-5

Abstract:

In order to assess the value of liver volumetry in cirrhosis and acute liver failure (ALF) patients, we explored the correlation between hepatic volume and severity of the hepatic diseases.to get a regression formula for standard liver volume (SLV) and BSA.It turned out that the mean liver volume of the control group was 1 058±337 cm3.In conclusion, the CTLV/SLV ratio, which reflects liver volume variations, correlates well with the liver

Keywords： liver volume variation     cirrhosis     acute liver failure (ALF)    

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The Human Microbiota in Health and Disease

Baohong Wang, Mingfei Yao, Longxian Lv, Zongxin Ling, Lanjuan Li

Engineering 2017, Volume 3, Issue 1,   Pages 71-82 doi: 10.1016/J.ENG.2017.01.008

Abstract: microbial role in basic biological processes and in the development and progression of major human diseasessuch as infectious diseases, liver diseases, gastrointestinal cancers, metabolic diseases, respiratorydiseases, mental or psychological diseases, and autoimmune diseases.

Keywords： Microbiome     Health     Infectious disease     Liver diseases     Gastrointestinal malignancy     Metabolic disorder     Microbiota    

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Title Author Date Type Operation

Autoimmune hepatitis

Farhad Sahebjam,John M. Vierling

Journal Article

γδ T cells in liver diseases

Xuefu Wang, Zhigang Tian

Journal Article

NKT cells in liver diseases

Shasha Zhu, Huimin Zhang, Li Bai

Journal Article

The critical importance of epigenetics in autoimmune-related skin diseases

Journal Article

Laparoscopic treatment of liver diseases in children

Jia Wei, Jiexiong Feng

Journal Article

Th17 Cells in autoimmune diseases

Lei Han,Jing Yang,Xiuwen Wang,Dan Li,Ling Lv,Bin Li

Journal Article

Natural killer cells in liver diseases

Meijuan Zheng, Haoyu Sun, Zhigang Tian

Journal Article

The Gut Microbiota, Tumorigenesis, and Liver Diseases

Guishuai Lv, Ningtao Cheng, Hongyang Wang

Journal Article

Human menstrual blood-derived stem cells alleviate autoimmune hepatitis via JNK/MAPK signaling pathway

Journal Article

Partial liver transplantation

Nianqiao GONG, Xiaoping CHEN

Journal Article

Diagnostic criteria of latent autoimmune diabetes in adults (LADA): a review and reflection

Yu Liao, Yufei Xiang, Zhiguang Zhou

Journal Article

Autoimmune regulator regulates autophagy in THP-1 human monocytes

Liang SHI, Li-Hua HU, Yi-Rong LI

Journal Article

The “Traditional Chinese medicine regulating liver regeneration” treatment plan for reducing mortalityof patients with hepatitis B-related liver failure based on real-world clinical data

Ling Dai, Xiang Gao, Zhihua Ye, Hanmin Li, Xin Yao, Dingbo Lu, Na Wu

Journal Article

Assessment of liver volume variation to evaluate liver function

Cong Tong, Xinsen Xu, Chang Liu, Tianzheng Zhang, Kai Qu

Journal Article

The Human Microbiota in Health and Disease

Baohong Wang, Mingfei Yao, Longxian Lv, Zongxin Ling, Lanjuan Li

Journal Article